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Weekly injection proven to reduce body weight by up to 22.5% in clinical trials
Dual action
Unlike earlier GLP-1 medications, Mounjaro (tirzepatide) activates two hormone receptors simultaneously. GLP-1 and GIP. This dual mechanism produces significantly greater appetite suppression and superior weight loss compared to semaglutide alone, as demonstrated in the SURMOUNT clinical trial programme.
0%
Average weight loss at 15mg (SURMOUNT-1, 72 weeks)
0%
of patients lost at least 5% body weight on tirzepatide 15mg
Dual action
Only licensed weight loss injection activating both GLP-1 and GIP
Clinical evidence
The SURMOUNT clinical trial programme enrolled over 4,500 participants globally. SURMOUNT-1, published in the New England Journal of Medicine in 2022, showed participants on tirzepatide 15mg lost an average of 22.5% of their body weight over 72 weeks, approximately 23.6kg, alongside lifestyle modifications. This is the largest average weight loss ever demonstrated for a licensed weight loss medication.
Jastreboff AM et al. NEJM 2022; NICE Technology Appraisal TA1026 (2024)
22.5%
average body weight loss at max dose (SURMOUNT-1, 72 weeks)
91%
of patients lost at least 5% of body weight on tirzepatide
4 wks
to reach consistent levels in the bloodstream from starting dose
2
hormone pathways targeted simultaneously. GLP-1 and GIP
Weight loss estimator
Enter your starting weight. Based on SURMOUNT-1 clinical trial averages, individual results vary.
What this is based on
The SURMOUNT-1 randomised controlled trial found patients taking tirzepatide 15mg alongside lifestyle changes lost an average of 22.5% of starting body weight over 72 weeks. Published in the New England Journal of Medicine, 2022.
IN ONE YEAR YOU COULD LOSE
20.3 kg
and reach approximately 69.8 kg
percentage lost
22.5%
target weight
69.8 kg
Based on average 22.5% body weight loss at 15mg in SURMOUNT-1 (Jastreboff AM et al., NEJM 2022). Results depend on dose reached, adherence, and individual response.
Check your eligibility. Start free consultationWhat's included
Prescribed Mounjaro pen at your approved dose
All injection needles included
For hygienic administration at every injection
Insulated pouches and ice gel packs, Royal Mail 48hr, £3.99
How it works
Unlike earlier GLP-1 medications that target a single hormone pathway, Mounjaro activates both GLP-1 and GIP receptors, producing significantly greater weight loss than semaglutide alone.
Start your consultationAppetite suppression
GLP-1 and GIP receptors in the brain work together to reduce hunger signals, so you feel satisfied with significantly smaller portions.
Slower gastric emptying
Food moves more slowly from your stomach, prolonging fullness after each meal and reducing the urge to eat between meals.
Improved metabolic function
Tirzepatide improves insulin sensitivity and acts directly on fat tissue via GIP receptors, promoting fat breakdown at a cellular level.
Titration
All patients start at 2.5mg. Dose increases every 4 weeks under pharmacist guidance based on tolerability.
Eligibility
Treatment may be suitable if your BMI is 30 or above, or 27 or above alongside a weight-related health condition. Our pharmacist will assess your full eligibility during the consultation.
Clinical evidence
SURMOUNT-1 · New England Journal of Medicine · 2022
"Tirzepatide represents a genuine step change in what is clinically achievable for patients managing their weight."
Jimah Alsaai MPharm
Superintendent Pharmacist · GPhC 2232652
WEIGHT LOSS OVER TIME
Mounjaro vs diet and exercise alone
Chart illustrative, based on SURMOUNT-1 trial trajectory. Diet & Exercise arm represents placebo + lifestyle comparator group.
HEADLINE RESULTS
22.5%
average body weight loss at maximum 15mg dose over 72 weeks
91%
of participants lost at least 5% of body weight
5×
more weight lost compared with diet and exercise alone
Jastreboff AM et al. N Engl J Med 2022;387:205-216. SURMOUNT-1 randomised, double-blind, placebo-controlled trial. n=2,539.
Start your consultationPricing
2.5mg
£129.99
£149.99
WELCOME20Per 4-week pen + £3.99 delivery
Start assessment5mg
£159.99
£179.99
WELCOME20Per 4-week pen + £3.99 delivery
Start assessment7.5mg
£219.99
£239.99
WELCOME20Per 4-week pen + £3.99 delivery
Start assessment10mg
£249.99
£269.99
WELCOME20Per 4-week pen + £3.99 delivery
Start assessment12.5mg
£259.99
£279.99
WELCOME20Per 4-week pen + £3.99 delivery
Start assessment15mg
£279.99
£299.99
WELCOME20Per 4-week pen + £3.99 delivery
Start assessmentNew patients save £20 on their first order with code WELCOME20, applied automatically at checkout.
New patients save £20 on their first order with code WELCOME20, applied automatically at checkout.
Side effects
Like all medicines, Mounjaro can cause side effects. Most are mild and improve as your body adjusts to the medication.
Very common (more than 1 in 10)
Nausea · Diarrhoea · Vomiting · Constipation · Decreased appetite
Common (up to 1 in 10)
Indigestion · Abdominal pain · Injection site reactions · Fatigue · Dizziness
Managing them
Starting at the lowest 2.5mg dose and increasing gradually significantly reduces the severity of side effects. Eating smaller meals and staying hydrated helps. Most people find side effects improve substantially after the first 4 to 8 weeks.
Pharmacist support
Our superintendent pharmacist reviews every consultation personally. If you have questions about eligibility, dosing, or side effects before you begin, you can request a callback during your consultation, or start now and our team will be in touch.

Jimah Alsaai MPharm
GPhC 2232652 · Superintendent Pharmacist
Mounjaro UK price comparison
Full retail prices per dose, no discount. Solira's WELCOME20 first-month price shown in green. Updated August 2026.
| Dose | Solira | Voy | Numan | Juniper | MedExpress | Boots | Superdrug |
|---|---|---|---|---|---|---|---|
| 2.5mgStarting dose | £149.99 £129.99 1st month w/ WELCOME20 Lowest here | ~£209 | £219 | ~£199 | £179.99 | £179 | £179 |
| 5mg | £179.99 £159.99 1st month w/ WELCOME20 Lowest here | ~£239 | £249 | ~£219 | £189.99 | £199 | £199 |
| 7.5mg | £239.99 £219.99 1st month w/ WELCOME20 Lowest here | ~£279 | £299 | ~£259 | ~£249.99 | £259 | £259 |
| 10mg | £269.99 £249.99 1st month w/ WELCOME20 Lowest here | ~£314 | £319 | ~£289 | £279.99 | £299 | £299 |
| 12.5mg | £279.99 £259.99 1st month w/ WELCOME20 Lowest here | ~£339 | £339 | ~£309 | ~£299.99 | £319 | £319 |
| 15mg | £299.99 £279.99 1st month w/ WELCOME20 Lowest here | ~£359 | £359 | ~£329 | £309.99 | £339 | £339 |
Notes: all prices in GBP for a 4-week supply. Solira's WELCOME20 first-month discount applies to new patients only. This comparison covers the named providers shown and is not a claim to be the lowest price in the UK market. "~" = price extrapolated from published competitor announcements and comparison sites. A blank cell means the dose is not currently offered by that provider.
Updated August 2026
FAQ
Most patients notice reduced appetite within the first week. Meaningful weight loss typically becomes visible from weeks 4 to 8. The clinical trials ran for 72 weeks, sustainable results take time.
Clinical evidence shows stopping treatment often leads to weight regain as the hormonal drivers of appetite return. Your prescriber will discuss your long-term plan at each review.
Alcohol is not directly contraindicated but adds calories, can worsen nausea, and may affect blood sugar. Moderate consumption is generally acceptable.
If within 4 days of your usual day, take it as soon as possible. If more than 4 days have passed, skip and resume your normal schedule the following week. Never take two doses in one week.
Store in the fridge (2°C to 8°C). Once removed it can be stored below 30°C for up to 21 days. Keep out of direct sunlight and away from children.
No. Ozempic (semaglutide) only activates GLP-1 receptors. Mounjaro activates both GLP-1 and GIP, producing greater weight loss. Wegovy is a higher-dose semaglutide licensed for weight management.
Mounjaro is a prescription-only medication issued at the clinical discretion of our prescriber. Individual results may vary. Lifestyle changes including improved diet and regular exercise are required alongside treatment. Clinical trial data cited is from published SURMOUNT trial results.