Mounjaro and Pregnancy: Trying for a Baby, When to Stop, and What to Do if You Are Pregnant

No. Mounjaro (tirzepatide) must not be used in pregnancy: the UK product information (revised August 2026) and the MHRA both advise against it, because there is not enough safety data from pregnant women and animal studies showed harm. If you are planning a baby, stop Mounjaro at least 1 month before you start trying and keep using contraception until then; if you find out you are pregnant while taking it, do not take another dose, and contact your GP or prescriber straight away.

The same applies to the other GLP-1 medicines we supply, each with its own gap before trying. This guide sets out why, how long to stop each one, what to do if a pregnancy comes first, and how we help you plan ahead.

It covers Mounjaro (tirzepatide), Wegovy injections and Wegovy tablets (semaglutide), and Foundayo (orforglipron). Other questions women ask us about these medicines are gathered on our page on women's health on weight-loss treatment.

Can you take Mounjaro while pregnant?

No. The UK product information says tirzepatide, the medicine in Mounjaro, should not be used during pregnancy, and it says the same of Wegovy, Wegovy tablets and Foundayo. The MHRA, the UK medicines regulator, says GLP-1 medicines should not be taken during pregnancy, just before trying to get pregnant, or while breastfeeding. There are three reasons.

• Not enough safety information. The MHRA says there is not enough safety data to know whether a GLP-1 medicine can harm a baby. The Mounjaro product information describes the data from pregnant women as none or limited, and for Foundayo there are no adequate studies in pregnancy.
• Animal studies. For all four medicines, studies in animals showed harmful effects on reproduction. The MHRA notes that more information is needed to know whether the same would happen in people.
• Weight loss is not a goal in pregnancy. NICE advises that trying to lose weight during pregnancy is not recommended, because of possible effects on the baby.

So the advice is precautionary. Harm in people has not been shown, but it has not been ruled out either, and that is why these medicines are stopped before a pregnancy rather than during one.

How long before trying for a baby should you stop Mounjaro?

Each medicine stays in your body for a while after the last dose, which the product information gives as the reason for a minimum gap between stopping and starting to try. The gap is counted from your last dose, and you keep using contraception all the way through it.

For the injections, the counselling we give every patient reads:

Pregnancy: these medicines must not be used in pregnancy. Stop and contact us or your GP immediately if you become pregnant. If planning pregnancy: stop Mounjaro at least 1 month before, Wegovy at least 2 months before.

Wegovy tablets contain the same medicine as the injection, and the gap is the same: at least 2 months. For Foundayo, the counselling we give reads:

Foundayo must not be used in pregnancy. If you become pregnant, stop treatment and contact your GP or prescriber immediately. Stop it at least 3 weeks before you try to conceive.

These are minimums: a longer gap is fine, a shorter one is not. Our guide on how long Mounjaro stays in your system explains why the gap for Mounjaro is a month.

Do you still need contraception after stopping?

Yes. The MHRA asks anyone who could become pregnant to use contraception while taking a GLP-1 medicine and for the whole wash-out period after it, which is the time between your last dose and starting to try. So do not stop your contraception on the day of your last dose. Keep it going until the gap in the table has passed.

If you use the contraceptive pill, the medicine matters. Mounjaro and Foundayo can make the pill less reliable for a few weeks after starting and after each dose increase, while Wegovy and Wegovy tablets need no extra precautions unless you have severe vomiting or diarrhoea. Rather than repeat it here, our guide to contraception and the pill on GLP-1 treatment sets this out medicine by medicine, with what to do if you are sick.

If you have found it hard to get pregnant in the past, do not rely on that as contraception now. The UK product information says the effect of these medicines on human fertility is not known. Our guide to Mounjaro and fertility explains what is and is not known.

What should you do if you find out you are pregnant on Mounjaro?

Do not take another dose. Then:

• Contact your GP or prescriber straight away. Tell them which medicine you take, your dose and the date of your last dose. If you already have a midwife, tell them too. If you have type 2 diabetes, say so at once: your blood sugar may rise when you stop, and other medicines are used for diabetes in pregnancy.
• Tell us at hello@withsolira.com, so we can stop any further supply and update your record.
• Start folic acid if you are not taking it already. The NHS advises 400 micrograms a day as soon as you find out you are pregnant, until 12 weeks. Some people need a higher dose, as set out below.
• Do not try to lose weight while you are pregnant. Your midwife can help with eating well and staying active during pregnancy.
• Read the UKTIS leaflet. The UK Teratology Information Service (UKTIS) is the UK's source of information on medicines in pregnancy. Its Bumps leaflet on GLP-1 medicines covers all four medicines in this guide, and your GP or midwife can get more detailed information from UKTIS. Its MyBump Portal lets you record your pregnancy to help build safety information for others.
• If you took Wegovy, its product information asks that any pregnancy is reported to the Novo Nordisk Pregnancy Registry, a UK study run by Imperial College Healthcare NHS Trust. You can register your interest on its website, or ask your GP or midwife to help.
• Report any problem you think a medicine may have caused, for you or your baby, through the MHRA Yellow Card scheme. You or your doctor can make a report.
• Return any unused pens or tablets to a pharmacy for safe disposal, and put used needles in your sharps bin.

Accidentally got pregnant on Mounjaro: what does the evidence say?

A pregnancy is often not confirmed until several weeks in, so some people find they took one or more doses before they knew. If that is you, here is what the UK sources say, without making it sound better or worse than it is.

UKTIS. Its leaflet, updated in September 2026, says that if a GLP-1 medicine was used by accident in early pregnancy, the information available suggests it does not harm the baby. That is based on studies of about 47,000 women, most of whom took a GLP-1 medicine before they realised they were pregnant and stopped soon afterwards. UKTIS says more research is needed to confirm this, and to find out whether there are any risks from use later in pregnancy.

The product information. It says there is little or no data from pregnant women, and that animal studies showed harmful effects on reproduction. That is why the advice is still to stop at once, rather than to finish a pen or a pack.

What happens next. UKTIS says no extra monitoring for major birth defects is needed after use in early pregnancy. As part of routine antenatal care, you will usually be offered a detailed scan at around 20 weeks. If you have type 2 diabetes or a high BMI, you may be offered more regular checks for those reasons.

UKTIS also gives the background risk that every pregnancy carries, whether or not a medicine is taken: about 1 in 5 pregnancies ends in miscarriage, and about 1 in 40 babies is born with a birth defect. Your GP or midwife can go through what the UKTIS information means for you.

Planning a pregnancy on Mounjaro: how do you plan ahead?

The easiest pregnancy to plan around treatment is one you tell us about early. Every patient agrees, before their first order, to tell us as soon as they start planning a pregnancy. Here is what we suggest.

• Tell us when you start planning. We will stop supply and note your record, so a reorder is not sent by mistake.
• Work back from when you want to start trying. Your last dose needs to be at least 1 month before for Mounjaro, 2 months for Wegovy injections or tablets, and 3 weeks for Foundayo. We can help you time your last order, so you are not left with medicine you cannot use.
• Keep your contraception going until that gap has passed.
• Start folic acid, ideally 3 months before you start trying, as below.
• Keep the habits that have worked for you. Appetite comes back as the medicine leaves your body, and some weight can return when treatment stops, especially if eating and activity habits slip. Our guide to what happens when you stop taking Mounjaro explains what to expect.
• Speak to your GP about any other medicines you take regularly. If you have type 2 diabetes, speak to your GP or diabetes team before you stop, so your diabetes care can be planned for pregnancy.

We do not supply any weight loss medicine while you are trying for a baby, pregnant or breastfeeding, and that includes orlistat, which is not a GLP-1 medicine. If you would like support with your weight before a pregnancy or after your baby, your GP can tell you about NHS weight management services in your area.

Which folic acid and vitamins do you need before and during pregnancy?

The NHS recommends 400 micrograms of folic acid every day when you are trying to get pregnant, ideally from 3 months before, and for the first 12 weeks of pregnancy. It lowers the chance of a neural tube defect such as spina bifida.

A higher BMI does not, on its own, mean you need more. NICE says people with a BMI of 25 or more who are planning a pregnancy do not need more than 400 micrograms a day, unless they have one of the reasons below. The NHS advises a higher dose of 5mg, prescribed by a GP, if:

• you have diabetes
• you or the baby's father has a neural tube defect, or a relative with one
• you have had a previous pregnancy affected by a neural tube defect
• you have a blood condition such as sickle cell anaemia or thalassaemia
• you take medicine for epilepsy or HIV

The NHS also advises 10 micrograms of vitamin D a day in pregnancy, from October to March, or all year for some people, and says not to take vitamin A (retinol) supplements or cod liver oil while pregnant. If you have had weight loss surgery, NICE advises asking your surgery unit for advice on folic acid and other vitamins before a pregnancy.

Can you take Mounjaro after pregnancy?

Please do not restart treatment while you are breastfeeding. The MHRA says GLP-1 medicines should not be taken while breastfeeding, and the product information for Wegovy, Wegovy tablets and Foundayo says the same. The Mounjaro product information now describes a small study that found very low or undetectable levels in breast milk, but the MHRA's guidance has not changed, and we follow it: we do not supply any weight loss medicine to someone who is breastfeeding. Our guide to Mounjaro and breastfeeding covers this in more detail, and the Breastfeeding Network has information on medicines while breastfeeding.

When you are ready to think about treatment again, our pharmacist will review you afresh. A break of three months or more means restarting from the lowest dose, so after a pregnancy you would start again from the first step. Our guide to restarting Mounjaro or Wegovy after a break explains how that works.

How do we check for pregnancy before every supply?

Our first consultation asks every woman: "Are you pregnant, breastfeeding, or actively trying to conceive?" We cannot supply weight loss medicines, injections or tablets, if you are. It also asks whether you take the oral contraceptive pill, and before you pay, you read the pregnancy and contraception advice for the medicine you have chosen and agree to tell us as soon as you start planning a pregnancy, and to stop the medicine and tell us straight away if you become pregnant.

Every reorder asks again: "Are you pregnant, planning pregnancy, or breastfeeding?" If you answer yes, the page tells you at once to stop your treatment and speak to your GP or midwife, and nothing is sent until our pharmacist has reviewed your answer. A GPhC-registered pharmacist reviews every consultation, and treatment stops if you become pregnant.

If you are not planning a pregnancy and would like to see whether treatment is right for you, the consultation is free and takes a few minutes: check if you are eligible. To compare the medicines first, see our weight loss treatments.